In contrast, Chang et al. discovered no significant difference in the allele frequency of TNF −1031C/T between patients with BD and controls in a Korean population, and the analysis of the influences of the TNF gene on various clinical manifestations of BD showed that TNF −1031C was not related to the presence of clinical features, such as oral and genital ulceration and uveitis [37]. The gene discussed is TNF; the disease is Behcet disease.