Some specific SNPs in the involved genes, such as RNASEL at 1q24-25 (also known as Hereditary Prostate Cancer gene 1 (HPC1)), have been related to an increased risk of developing prostate cancer (Alvarez-Cubero et al. 2012; Agalliu et al. 2010; Meyer et al. 2010). The gene discussed is RNASEL; the disease is prostate carcinoma.