We did not detect any expression of TIM-3 and CD137 molecules and their respective ligands Galectin-9 and CD137L on the surface of ID8 ovarian cancer cells (data not shown), excluding the possibility that inhibition of ID8 tumor growth in vivo is directly mediated by anti-TIM-3 or anti-CD137 mAb. The gene discussed is TNFRSF9; the disease is neoplasm.