More than half (62%) of the clusters of CNHCs-BF-type and all of the CNHC of the -MF and -UMF types found on the filters analysed with antibodies against CD31 were positive, whereas only 6% of the CNHC-UMF- and none of the CNHC-BF clusters were positive on the filters stained for the RCC marker CAIX [36,37]. The gene discussed is PECAM1; the disease is renal cell adenocarcinoma.