CD8A and neoplasm: Accordingly, univariate Cox hazard regression analysis revealed a significant survival advantage of patients with high CD8+ cell tumor infiltration (cutoff median) in patients with residual tumor (high vs. low: HR = 0.46, 95% CI 0.24-0.88, p = 0.020), whereas CD8+ cell infiltration was not of prognostic value in patients without residual tumor (high vs. low: HR = 0.96, 95% CI 0.57-1.61, p = 0.864).