DNAJC5 and malaria: Then, those lineages were used to investigate the evolution of three malarial antigens: 1) the gene encoding the circumsporozoite protein (CSP), a pre-erythrocytic malaria vaccine antigen; 2) the gene encoding MSP2, an erythrocytic stage malaria vaccine antigen; and 3) the var2CSA gene that has been associated with malaria in pregnancy.