Inactivating mutations of the Slc12A6 gene encoding KCC3 are the cause of a complex neurological disease known as agenesis of the corpus callosum with peripheral neuropathy, also referred as Andermann syndrome (Online Mendelian Inheritance in Man (OMIM) 218000) (4–6). Here, SLC12A6 is linked to Corpus callosum agenesis - neuronopathy.