Although this study does not show a synergistic anti-tumor effect of cAT-MSC-IFN-β with cisplatin on canine melanoma cells in vitro, we previously demonstrated the synergistic anti-tumor effects of cAT-MSC-IFN-β with cisplatin on mouse melanoma in vitro and in vivo[30]. This evidence concerns the gene IFNB1 and neoplasm.