GSTO2 and tarsal-carpal coalition syndrome: The Kaplan-Meier survival analysis in the whole group with muscle invasive TCC demonstrated that the GSTO2 Asp142Asp homozygotes had two times shorter mean survival in comparison with patients with at least one Asn allele (23.8±4.2 vs. 40.8±2.7 months, respectively; P = 0.008, Fig 4a).