LTBI subjects from Uganda (MAK) had significantly higher IFN-γ levels compared to TB following TB10.3 and TB10.4 stimulation (p<0.0001 for both) in HIV- subjects (Figure 5A) and following EC (p=0.0342) and TB10.3 (0=0.0013) stimulation in HIV+ subjects (Figure 5B). Here, IFNG is linked to tuberculosis.