ACKR3 and neoplasm: Importantly, the expression pattern of CXCR7 in 143B-LacZ-EV and 143B-LacZ-HA-X7 cell-derived tumors was indistinguishable from that observed in the respective cells in vitro, with non-detectable CXCR7 expression in 143B-LacZ-EV cell-derived tumors and robust expression in 143B-LacZ-HA-X7 cell-derived tumor tissue (Figure S1A).