Finally, since we believe that single allelic variants themselves are not sufficient to predict, in many cases, the predisposition to the risk of PCa, we evaluated GLO1 A111E polymorphism in combination with other oxidative stress control-related polymorphic genes, that we previously found to be associated with the risk of PCa in a case/control study [27], whose BPH and PCa cohorts has been here included in the new enlarged populations. This evidence concerns the gene GLO1 and posterior cortical atrophy.