Of all SCAs, SCA type 8 (SCA8) presents a molecular trait that distinguishes it from other dominant ataxias: its involving a CTG repeat expansion in the ATXN8OS (ataxin 8 opposite strand) gene and a CAG repeat expansion in the overlapping ATXN8 (ataxin 8) gene [2]. The gene discussed is ATXN8; the disease is Ataxia.