SLC7A2 and colorectal carcinoma: As shown in Figure 3, when more than 3-fold over-expression was set as the cut-off value, CAT-1 gene expression was elevated in CRC tissues in 86 of 122 patients (70.5%), in whom the expression level of CAT-1 in CRC tissues was 3.6- to 181-fold higher than in normal colon tissues, whereas expression of SLC7A2A and SLC7A2B was elevated in only 6/122 and 12/122 (4.9 and 9.8%) patients respectively.