NPY and epilepsy: Additionally, exogenously administered NPY has been shown to suppress seizure activity in cortical and hippocampal slices in vitro [26], [27], [28], in experimental models of epilepsy, including the Genetic Absence Epilepsy Rats from Strasbourg (GAERS) model of genetic generalised epilepsy [13], [18], [29], after kainic acid-induced seizures [30] and chronic infusions of NPY delays amygdala kindling epileptogenesis [31].