Importantly, based on the results obtained using the model of PGN induced tolerance and subsequent transcriptome analysis, we were able to identify genes with altered expression in inflammatory diseases such as psoriasis (this study) and TNBS-induced rat model of colitis (unpublished), which underlies the relevance of the in vitro model for further characterization of IFN-primed iDCs. Here, IFNA1 is linked to psoriasis.