However, the percentage of displaying positive staining was significantly higher in glioblastomas than in grade III gliomas, for all the proteins tested (Figure 2, EDN/RB: p<0.001, p60/CAF-1: p<0.001, PDLI4: p=0.007 and HJURP: p<0.005). Here, CHAF1B is linked to central nervous system cancer.