GPX1 and neoplasm: In contrast, rs3877899 was not associated with risk of a non-ductal tumour; however, women homozygous TT for rs1050450 (GPX1, Leu variant) had an increased risk of having a non-ductal tumour (1.88 [1.08–3.28], p = 0.027) but it should be noted that there were few individuals with this genotype.