Our results showed significant evidence for 2 AD susceptibility SNPs (A2M V1000I polymorphism (OR = 1.26, 95% CI = 1.07–1.49, P = 0.007), ABCA2 rs908832 polymorphism (OR = 1.55, 95% CI = 1.12–2.16, P = 0.009). The gene discussed is ABCA2; the disease is Alzheimer disease.