To verify the role of phosphorylation of FAK in regulation of c-fos, expression of c-fos mRNA induced by G1 (a GPR30 agonist) in the presence or absence of FAK inhibitor 14 was determined by Taqman real-time quantitative polymerase chain reaction (PCR) in endometrial cancer cells. Here, GPER1 is linked to endometrial cancer.