The inducibility of the UPR in DTT-treated U87MG cells (and those expressing EGFR or the oncogenic mutated EGFRvIII, which is an in-frame deletion mutant removing 801 base pairs of exons 2-7 [42], yielding a constitutively activated receptor) led us to compare those cells to another tumor cell line, HeLa, in terms of response the UPR inducer DTT. Here, EGFR is linked to neoplasm.