This is within the range of other phenotypic markers that were linked to patient survival, including PTEN (1.57- fold increase in proneural vs. proliferative—loss of PTEN is common in high grade gliomas and generally indicative of shorter survival) and VEGF2 (1.6-fold increase in mesenchymal vs. proneural). The gene discussed is PTEN; the disease is central nervous system cancer.