Cell lines/tumors examined included U87MG, an established (human) patient-derived glioma line and U87+EGFR, which are parent U87MG cells stably overexpressing the wild type EGFR receptor (also referred to as U87-wtt); EGFR overexpression is considered a hallmark of gliomas [40], and this cell line is a popular model for that situation. This evidence concerns the gene EGFR and central nervous system cancer.