NOX5 and infection: Co-silencing NOX5 and puc (Figure 2D, Table S3) increased the median number of oocysts/midgut from 0 to 10 (p<0.0001; KS test) to the same level as the dsLacZ control, and the prevalence of infection from 22% to 88% (p<0.0001; χ2 test).