E2F1 and breast carcinoma: As expected, concordance analysis between ER+ and ER− breast cancer DRGEPs and TREG signatures of ERα and E2F1 activity demonstrated involvement of E2F1 regulation in both DRGEPs (p-value = 7.0×10−14 for ER+ and p-value = 1.3×10−72 for ER−).