Interestingly, qRT-PCR analysis on DRGs from tumour-bearing mice revealed that at PID-8, a time point at which we had initially observed that miRNA-1a-3p is upregulated (Fig 1, panel E), the expression levels of Clcn3 mRNA are significantly lower than levels in basal state or sham controls (Fig 5, panels B and C; two-tailed t-test assuming equal variances). The gene discussed is CLCN3; the disease is neoplasm.