Additionally, nevirapine induced the expression of cell-type-specificdifferentiation markers in many transformed cell lines, including the geneticallyabnormal acute myeloid leukemia (AML) cell lines with t(15;17)PML/RARA and t(8;21) AML1/ETO and primaryblasts from AML patients [29,37,38]. This evidence concerns the gene RUNX1 and acute myeloid leukemia.