VDR and infection: Previous studies have characterized a role for two heterodimeric partners of RXR in the control of Leishmania major infection, the vitamin D receptor (VDR) (Ehrchen et al., 2007, Whitcomb et al., 2012) and the liver X receptor (LXR) (Bruhn et al., 2010), with deficiency in either receptor resulting in enhanced resistance to infection.