GPT and Hepatic fibrosis: However, after adjustment for gender, age, weight, HCV genotype, viral load, serum alanine aminotransferase level, and liver fibrosis stage at pretreatment, adherence to (peg) interferon alpha, ribavirin or combination of them, only adherence to ribavirin during the first six months (OR = 3.295, 95% CI = 1.184-9.168, P = 0.022) was significantly associated with achieving ETR or SVR.