Apart from Li-Fraumeni Syndrome, these include Cowden Disease (PTEN) [9,10], Peutz-Jeghers Syndrome (LKB1/STK11) [11,12], Lynch Syndrome (MSH2,MLH1) [13], Bloom’s Syndrome (BLM) [14] and Ataxia-Telangiectasia (ATM) [15]. The gene discussed is BLM; the disease is Bloom syndrome.