Furthermore, Gfi1 has been shown to cooperate with a number of oncoproteins including Myc, Pim-1, E2A-HLF and the intracellular form of Notch1 (ICN) in the development of lymphoma and ALL [8], [9], [14], [18], [19]. The gene discussed is GFI1; the disease is acute lymphoblastic leukemia.