HOXB8 and melanoma: Ensembl genome browser localized this sequence to the (-) strand of a 2630 bp non-coding RNA gene (RP11-35H14.16), now a recognized lincRNA (UCSC genome browser ID AK025239), which corresponded to HOXB8-B9 gene, this locus includes the coding sequence for miR-196a, targeting HOX-C8 mRNA, also down-regulated in melanoma compared to human melanocytes [39].