Interestingly, IPA analysis for the NF-κB signalling showed CD40LG, LCK, LTBR and TNFSF11 were present in the down-regulated probesets and EIF2AK2 and MYD88 were present in the up-regulated probesets of canine DLBCL. The gene discussed is TNFSF11; the disease is diffuse large B-cell lymphoma.