Some of the important signalling pathways enriched in the differentially expressed probesets in DLBCL are IL-10, p53, IL-6, NF-κB, IL-2, PI3K, BRCA1 in DNA damage response, NOTCH and PI3K/AKT signalling pathways, which are common to the canine system. Here, IL6 is linked to diffuse large B-cell lymphoma.