S100A4 and neoplasm: The proliferation assay showed no differences between both cell types (data not shown), but after subcutaneous implantation we observed a dramatically reduced rate of tumor growth for non-expressing S100A4 MiaPACA-2 cells; only 5 out of the 15 animals developed tiny tumors compared with the S100A4 expressing counterpart where all 15 animals developed big tumors (Fig. 6A).