EGFR and cancer: Some of them have been used as cancer drug targets, for example, ERBB2 (v-erb-b2, erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)), and EGFR (epidermal growth factor receptor) are targets in breast cancer treatment [48]; other affected nodes may be potential drug target for cancer treatment.