ERCC1 and non-small cell lung carcinoma: For example, Takenaka et al. demonstrated that ERCC1 rs3213986 SNP might influence the NSCLC prognosis regardless of the ERCC1 expression and platinum sensitivity in 122 Japanese NSCLC patients who underwent a complete resection [27]; however, KimCurran's study showed that there was lack of correlation between ERCC1 C8092A (rs3212986) SNP and OS or efficacy/toxicity of platinum-based chemotherapy in 300 Chinese NSCLC patients treated with chemotherapy [28].