Eight weeks after TAC, the left ventricular mass to tibia length-ratio (LVM/TL; Fig. 1B) was significantly lower (13.1±0.8 vs. 15.1±0.8 mg/mm) and the EF (Fig. 1D) better preserved (20.4±2.8 vs. 10.7±1.9%) in CYP2J2-TG compared to WT mice (compare Table S2 for the full set of echocardiographic data). The gene discussed is CYP2J2; the disease is persistent truncus arteriosus.