In this study, we examined the frequencies of Th17 and Th1 cells and the concentrations of related cytokines (IL-17A, IL-6, TGF-β1, and IFN-γ) in BM or PB of patients with different AML stages and controls and evaluated their involvement in the pathogenesis and progression of AML. This evidence concerns the gene IFNG and acute myeloid leukemia.