In contrast, tumor expression of Glut-1, CAIX and MCT-4 was lowest in luminal A and B. Luminal type tumors tend to show a lower grade, lower mitotic index and less necrosis than the HER2 type or TNBC, suggesting nonactive metabolic status of the tumor, which was supported by the results of IHC. This evidence concerns the gene CA9 and neoplasm.