Activated NF-κB is known to be involved in the regulation of a wide array of genes; among them are those in the infection, adhesion, cell cycle, apoptosis, survival and inflammatory process by upregulating the transcriptional levels of multiple genes, including IL-1β, TNF-α, IL-6, cyclooxygenase-2 (COX-2) and matrix metalloproteinases (MMPs) [29-31]. The gene discussed is PTGS2; the disease is infection.