Thus, in an effort to determine the persistence of 599 peptide-mediated silencing of CIP2A in oral cancer cells over time, a Western blot analyses of CIP2A protein expression levels in CAL 27 and SCC-25 oral cancer cells 1, 3, 5, 7, and 9 days post-treatment with 599 peptide complexed to either siNT or siCIP2A at a 50∶1 peptide-to-siRNA molar ratio were performed (Fig. 7A). Here, CIP2A is linked to lip and oral cavity carcinoma.