A disease characterized by progressive extraocular muscle weakness - horizontal gaze palsy with progressive scoliosis - is also associated with both cardiomyopathy and limb-girdle muscular dystrophy based on a predicted interaction between TCAP and ROBO3, though limb-girdle muscle weakness is not directly associated with this disorder in the literature[26]. The gene discussed is TCAP; the disease is cardiomyopathy.