Its relationship to cardiomyopathy and limb-girdle muscular dystrophy is indicated by a predicted interaction between TCAP and ROBO2. Interestingly, although VUR is not associated with disorders of the striated or cardiac muscle, it has been observed to co-occur with visceral myopathy in cases of Chronic Intestinal Pseudo Obstruction and Berdon Syndrome[27]. This evidence concerns the gene ROBO2 and limb-girdle muscular dystrophy.