A small number of studies have searched for and detected serum biomarkers of inflammation in patients with upper extremity musculoskeletal disorders of short duration (<3 months), including C-reactive protein, interleukin- 6 (IL-6), tumor necrosis factor-alpha (TNF-α), and members of the IL-1 family [2], [3], [4]. The gene discussed is IL1B; the disease is musculoskeletal system disorder.