Gudmundsson et al. (2009) recently conducted a genome-wide association study (GWAS) of thyroid cancer cases; they found that a variant predisposes individuals from European populations to thyroid cancer; this variant is located on 14q13.3 near thyroid transcription factor-1 (TTF1), which is also called NKX2.1. This evidence concerns the gene NKX2-1 and thyroid cancer.