FAS and cancer: The results of the overall meta-analysis suggested a decreased association between the FAS-1377G/A SNP and cancer susceptibility (Homozygote comparison: OR = 0.86, 95% CI = 0.78-0.96, Pheterogeneity = 0.004, P = 0.006, dominant model: OR = 0.85, 95% CI = 0.78-0.94, Pheterogeneity = 0.010, P = 0.001 and allelic contrast: OR = 0.95, 95% CI = 0.91-1.00, Pheterogeneity = 0.000, P = 0.038).