We reasoned that siRNA knock-down of the proteins that bind to the splicing silencer at SD3632 should induce HPV-16 late gene expression if these proteins were suppressing SD3632 in the cervical cancer cells and therefore transfected the C33A2 reporter cell line with siRNAs against all known splice variants of hnRNP D, hnRNP DL, hnRNP AB or hnRNP A2/B1. The gene discussed is HNRNPDL; the disease is cervical carcinoma.