SLX4 and Fanconi anemia: A Fanconi anemia (FA) protein, SLX4 (or BTBD12 or FANCP), is a molecular scaffold that interacts with structure-specific endonucleases XPF-ERCC1, MUS81-EME1, and SLX1 (Fekairi et al., 2009; Kim et al., 2013; Muñoz et al., 2009; Svendsen et al., 2009).