MAPT and frontotemporal dementia: Around 20% of patients within the FTD spectrum have an autosomal dominant pattern of inheritance with mutations in the genes progranulin (GRN), microtubule-associated protein tau (MAPT) and chromosome 9 open reading frame (C9orf72) being the commonest causes (Rohrer et al., 2009, Rohrer and Warren, 2011).