While the hypermigration of SSc monocytes was similar to the hypermigration of TGFβ-treated monocytes in that both were inhibited by CSD and Cav-BC, they differed dramatically in their response to Cav-A which inhibited TGFβ-induced monocyte hypermigration but slightly increased SSc monocyte hypermigration (Figure 2, Table 3). The gene discussed is CA5A; the disease is systemic sclerosis.