EGFR and non-small cell lung carcinoma: With proven efficacy and mild toxicity observed with the epidermal growth factor receptor (EGFR) pathway targeting agents (monoclonal antibodies and tyrosine kinase inhibitors) for the treatment of advanced NSCLC, these agents seem ideal to explore as alternatives to cytotoxic chemotherapeutic agents in the treatment of stage III NSCLC patients with poor-risk features.