TMEM43 and Emery-Dreifuss muscular dystrophy: Loss of emerin, mutations in emerin-associated proteins (A-type lamins, nesprin-1, nesprin-2, LUMA) or mutations in transcription factor FHL1 are all genetically linked to Emery-Dreifuss muscular dystrophy (EDMD) (Meinke, Nguyen & Wehnert, 2011).