CXCL8 and malignant colon neoplasm: First, we observed that starvation of cells from extracellular glutamine sources alone was able to induce the secretion of IL-8 by HCT116 (p<0.001) and DLD-1 (p<0.001) colon cancer cells (Figure 6A and Figure 6B), although at lower levels compared to H. bilis infection.